The residential and commercial area of Andheri is situated next to the Western Express Highway. This Locality has been divided into Andheri East and Andheri West by the Mumbai Suburban Railway Network's western line. Andheri is a popular business destination due to its superior social infrastructure, good connectivity, and abundance of commercial businesses.

Andheri Railway Station, the Western Express Highway, SV Road, Link Road, and BEST Bus Network provide excellent connections to various areas of Mumbai. Additionally, it is connected to the east and west by the operating Line 1, which runs between Versova, Andheri, and Ghatkopar. Additionally, Andheri is only 3 kilometers from the Chhatrapati Shivaji International Airport.

Andheri is Mumbai's major business district and has several important job hubs, including Santacruz Electronic Export Processing Zone, Marol Industrial Estate, Bandra Kurla Complex, and Chakala Industrial Area, which are all within a 15-kilometer radius.

The area has a number of malls that offer leisure space. DB Mall, Fun Republic, Crystal Point, Infiniti Mall, Andheri West Market, and Citi Mall are a few of the well-known ones. With PGs like Zolo and EZYPG, it has some housing colonies nearby like Vijaynagar Sahanivas Society, Kalpita Enclave, etc. Thus, Andheri is an excellent workplace that promotes work-life harmony.